Dimethyl sulfate is a chemical compound with formula (CH3O)2SO2. As the diester of methanol and sulfuric acid, its formula is often written as (CH3)2SO4 or Me2SO4, where CH3 or Me is methyl. Me2SO4 is mainly used as a methylating agent in organic synthesis.
Dimethyl sulphate (DMS) is an innocuous appearing, widely used, and highly toxic chemical. It is used both as a methylating agent in industrial chemical synthesis and in medical laboratories for chemical cleavage of DNA. It is readily absorbed through the skin, mucous membranes, and gastrointestinal tract.
The maximum daily intake of the potential genotoxic impurities should not exceed 1.5 μg per person per day by taking the highest dose.
The designations employed and the presentation of the material in this publication Analytical methods Dimethyl sulfate (DMS) is a very slightly odorous.
